Custom Compounding

Custom Compounding Information

In 1938, when the Food, Drug and Cosmetic Act was passed, very few dosage forms were available and pharmacists compounded more than 250 million prescriptions annually. Nearly all of those prescriptions were compounded from bulk materials. Through the years, technical advancements in compounding equipment have allowed pharmacists to meet the growing needs of patients.

Today, a custom compound is prepared from pure, pharmaceutical-grade raw materials in accordance with a physician’s prescription, based on an individual patient’s needs. The basis of the compounding profession of pharmacy has always been the “triad,” the patient-physician-pharmacist relationship. Through this relationship, patient needs are determined by a physician, who chooses a treatment regimen that may include a compounded medication. All ingredients of compounds meet strict guidelines to ensure safety and purity.

In light of the recent media coverage pertaining to the safety, quality, and compliance standards within compounding pharmacies, College Pharmacy wants to reassure our valued healthcare practitioners and patients that College Pharmacy has the right people, processes, procedures, and licensing in place to provide safe, quality, and consistent sterile and non-sterile preparations.

Custom compounding prescriptions requires a trained staff of pharmacists and technicians to prepare compounded medications to strict standards, the right equipment, and specialized processes and facilities.

Did you know that 30 to 40 million prescriptions are custom compounded each year? Why? Because each patient’s health and wellness needs are different, and sometimes the medication that’s available off the shelf won’t do. Some reasons you might need a custom-compounded medication:

  • The medication you need for your condition is discontinued.
  • You are allergic to a preservative, dye or binder that’s part of the medication you need.
  • You need a tailored dosage strength of a medication (for example, infants need lower dosages).
  • You can’t take the medication you need in the form in which it’s readily available (e.g., pills are difficult to swallow).
  • You need to change the flavor of the medication you require so that you, or your child or loved one, can take it.
  • You need a new treatment when other readily available ones have failed.
  • Your pet needs a medication that must be compounded.

If you feel you could benefit from a custom compounded prescription, College Pharmacy is here to help answer your questions. We will work with your healthcare practitioner to find a solution to your health and wellness needs.

What is Custom Compounding?

A customized medication prepared by a pharmacist according to a doctor’s specifications to meet an individual patient’s need. Pharmacists make medications from scratch using raw materials, powders and devices.

Preservative-Free and Allergy-Free Formulations

We are able to compound medications without the excipients and preservatives found in most commercial preparations. Suitable replacements free of color, starch, yeast, sugar and preservatives are easily formulated.

Discontinued Medicines

Hundreds of medicines are voluntarily withdrawn from the marketplace each year. A needed treatment may not be available due to a small market share or lack of profitability. A compounded replacement may be possible.

Dosage Variation

A tablet or capsule may need to be converted into a liquid, suppository, cream, or gel form. The exact dosage, or the ideal dosage a patient needs, may not be commercially available. Compounding can provide any dosage form the patient needs.

Medicines Not Commercially Available

Many formulations will never be commercially developed due to difficulty in obtaining patents and lack of market demand. Compounding allows for medical treatments that otherwise may not be possible.

Custom Dosage Forms & Sterile Compounding

College Pharmacy’s comprehensive compounding experience and state-of-the-art facility allows us to compound both traditional and advanced dosage forms. College Pharmacy’s compounding practices are both USP 795 and 797 compliant. Our testing protocol includes: potency, sterility, endotoxin, and fungal testing. Our sterile formulations are compounded in a state-of-the-art clean room and ISO 8 compounding lab that was fully renovated and updated in the summer of 2014.

Sterile Compounding Services

It is the compounding process, attention to detail, and the quality of the components that makes our compounded formulations exceptional. Nowhere else is this exemplified more than in our Sterile Compounding Services. College Pharmacy has a state-of-the-art ISO 8 compounding lab where all sterile formulations are compounded by specially trained pharmacists and compounding technicians using advanced techniques and equipment.

  • Testing: Potency, Sterility, Endotoxin, Fungal
  • Certificates of Analysis Available
  • MSDS Sheets Available

The list below is a small sample of compounded sterile injectable categories. Contact us directly for additional information about formulations, size, strength, preservative or preservative-free formulations, and pricing.

  • IV Protocols (Myers’ Cocktail, Super Immuno, Gaby Formula, etc)
  • Vitamins
  • Minerals
  • Amino Acids
  • Chelation Therapy / Heavy Metal Detox
  • Hormones
  • Urological
  • Neurotransmitters
  • Prolotherapy
  • Mesotherapy
  • Sclerotherapy

In addition to our compounding services, College Pharmacy also supplies commercial injectables to healthcare practitioners and patients. Please note: by law, compounding pharmacies cannot compound those items that are commercially available.

Custom Dosage Forms

One of the advantages of using a compounding pharmacy to fill your prescription needs is in the variety of dosage forms available. While traditional oral routes of administration are available, advanced dosage forms may increase patient compliance and treatment efficacy. The list below includes a sample of some of the dosage forms that College Pharmacy compounds.

Fused Pellet Implant: Inserted subcutaneously every 3 to 5 months. This route provides very constant hormone levels. Pellet implant formulations include: Estradiol, Testosterone, Biest, Pregnenolone, Progesterone, DHEA, Testosterone / Anastrozole.

Lipid Matrix Sublingual Tablets: Sublingual tablets are conveniently placed under the tongue for sublingual absorption and are not subject to first-pass metabolism by the liver. College Pharmacy’s sublingual tablet formulation incorporates lipid matrix dosing technology.

Percutaneous Gel: The skin acts as a reservoir, slowly releasing hormones from its microcirculation into the main circulation continuously over a 24-hour period. Percutaneous Gel is extremely hypoallergenic and compliance is very good due to its common once-a-day dosing.

Additional Compounded Dosage Form Examples:

  • PLO Gels & Creams
  • Topical Creams
  • Thick Gel
  • Suppositories (Rectal & Vaginal)
  • Ointments
  • Powder & Oil-Filled Capsules
  • Nasal Spray & Gel
  • Sublingual Drops
  • Ophthalmic Drops
  • Topical Sprays
  • Lip Balms
  • Lollipops
  • Nebulized Powders
  • Chemical Peals
  • Solutions
  • Suspensions
  • Mouth Rinse
  • Emollients
  • Oral capsules

Custom Compounding Links & Resources

Custom Compounding In Demand (PDF Download)

College Pharmacy Practitioner's Compounding Quick Guide (PDF Download)

International Academy of Compounding Pharmacists